of this effort involves allocating money to fund large, collaborative research groups that will conduct pharmacogenetics studies. "DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity". Director, Dr Soram Khalsa Medical; Institute, East-West Medical Research. Scientific American Magazine (August i'm almost finished with my research paper 2005).
Pharmacogenomics, however, is a broader term for the study of genomic influence on drug response, often using high-throughput approaches such as sequencing, single nucleotide polymorphism chip, expression profiling, and proteomics. Identical Twins: twins developed from a single fertilized ovum and therefore identical in genetic make-up at the time of conception, meaning they have 100 of their genes in common.
Why does it matter? For them, genotype predicts clinical outcome, a prerequisite for an effective pharmacogenetic test. A b Breckenridge A, Lindpaintner K, Lipton P, McLeod H, Rothstein M, Wallace H (September 2004). Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W (November 2001). Until this study in 2005, we only knew about the inflammation of the retinal tissue causing AMD, not the genes responsible. Utah.edu/units/pharma/ Pharmacogenomics: Drugs Designed for You, an accessible and comprehensive look at pharmacogenomics research, from the University of Utah's Genetic Science Learning Center * ED-B70183414B7F0000 A Drug to Call One's Own : Will medicine finally get personal? Such researchers then look to see what, if any, changes occurred in the mice's physiology, or in the growth characteristics of the cell cultures, as a result.
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